Acaluxen (Acalabrutinib) 100 mg Capsules

Indicated for the treatment of adult patients with:

• 🔹 Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL): Both treatment-naive and relapsed/refractory patients.
• 🔹 Mantle Cell Lymphoma (MCL): For patients who have received at least one prior therapy.

Packaging: 100 mg capsules.

⚠️ ADMINISTRATION PROTOCOL:

• Recommended Dose: 100 mg orally twice daily (approximately every 12 hours).
• Food Intake: Can be taken with or without food.
• Important Warning: ⛔ Avoid taking with proton pump inhibitors (PPIs) like omeprazole, as gastric acid is needed for absorption.
• Administration: Swallow whole with water. Do not chew, crush, or open capsules.
• Supply: One pack (60 caps) provides a full 30-day supply.

• Hypersensitivity to Acalabrutinib.
• Pregnancy and breastfeeding (risk of fetal harm).
• Severe bleeding disorders.
• Active severe infections.

Common adverse reactions include:

• 🤯 Headache: Very common (often manageable and diminishes over time).
• 🩸 Hematologic: Bruising, increased risk of bleeding/hemorrhage, neutropenia.
• 📉 Gastrointestinal: Diarrhea, nausea.
• 🦠 Infections: Upper respiratory tract infections.