Cerixen Capsules — Ceritinib 150 mg (90 Caps) Everest

Prescribed by oncologists for the treatment of adult patients with:

• 🔹 Non-Small Cell Lung Cancer (NSCLC): Metastatic ALK-positive NSCLC as detected by an FDA-approved test.

Sales Unit: Bottle in a box containing 90 capsules (150 mg strength). This provides exactly a 30-day supply.

⚠️ APPLICATION INSTRUCTIONS:

• Standard Dosage: 450 mg (three 150 mg capsules) taken orally once daily.
• Administration: Take with food. Swallow capsules whole with water. Taking with food improves absorption and reduces stomach upset.
• Dietary Warning: Avoid grapefruit and grapefruit juice, as they can dangerously increase drug levels in the blood. Do not chew or crush capsules.
• ✋ Missed Dose: Make up the dose unless the next scheduled dose is within 12 hours.

• ⛔ Pregnancy & Breastfeeding: Strictly contraindicated. Effective contraception is required during treatment and for 3 months after.
• Hypersensitivity to Ceritinib.
• Congenital Long QT Syndrome.
• Severe hepatic impairment requires dose adjustment.

Monitoring of liver enzymes, fasting glucose, and ECG is required. Potential side effects include:

• 🤢 Gastrointestinal: Diarrhea, nausea, vomiting (very common). Taking with food mitigates severity.
• 🔶 Hepatotoxicity: Elevated liver enzymes (ALT/AST).
• 🥗 Metabolic: Hyperglycemia (high blood sugar), decreased appetite.
• ❤️ Cardiac: Bradycardia (slow heart rate), QT prolongation.
• 💤 General: Fatigue, rash.