Evermil (Everolimus) 10 mg

Indicated for the treatment of:

• Advanced Renal Cell Carcinoma (RCC): After failure of sunitinib or sorafenib.
• Breast Cancer: HR-positive, HER2-negative advanced breast cancer (in combination with Exemestane).
• Neuroendocrine Tumors (NET): Of pancreatic, gastrointestinal, or lung origin.

Strength: 10 mg tablet.

Standard Dosage: 10 mg once daily.

⚠️ Administration Instructions:

• Take at the same time every day.
• Take consistently either with food or without food (do not alternate).
• Swallow whole with a glass of water. Do not crush.

• Severe hepatic impairment (requires dose reduction).
• Pregnancy and breastfeeding.
• Known hypersensitivity to rapamycin derivatives.
• Uncontrolled active infections.

Most Common: Oral Stomatitis (Mouth Ulcers).

Very common within the first 8 weeks. Tip: Use alcohol-free mouthwash or salt/baking soda rinses daily to prevent severity.

Other risks:

• Non-infectious Pneumonitis: Watch for new cough or shortness of breath.
• Rash, fatigue, and diarrhea.
• Increased risk of infections (immunosuppression).