Gilternib Tablets — Gilteritinib 40 mg (90 Tabs) Everest

Prescribed by hematologists/oncologists for adult patients with:

• 🔹 Acute Myeloid Leukemia (AML): Relapsed or refractory AML with a confirmed FLT3 mutation.

Sales Unit: Bottle containing 90 film-coated tablets (40 mg strength). Typically, one bottle lasts for 30 days.

⚠️ APPLICATION INSTRUCTIONS:

• Standard Dosage: 120 mg (3 tablets of 40 mg) taken orally once daily.
• Administration: Swallow tablets whole with water at the same time each day. Do not break or chew. Can be taken with or without food.
• Duration: Continue treatment as long as clinical benefit is observed or until hematopoietic stem cell transplantation (HSCT).
• ✋ Missed Dose: Take as soon as possible on the same day. Resume normal schedule the next day. Do not double the dose.

• ⛔ Pregnancy & Breastfeeding: Contraindicated. Can cause fetal harm. Effective contraception is mandatory.
• Hypersensitivity to Gilteritinib.
• Long QT Syndrome (history of).
• Pediatric patients (safety not established).
• Severe hepatic impairment.

Strict medical monitoring is required. Potential side effects include:

• ⚠️ Differentiation Syndrome: A serious condition (fever, dyspnea, fluid retention) caused by rapid cell maturation. Seek immediate medical help.
• 🩸 Liver: Elevated transaminases (ALT/AST).
• ❤️ Cardiac: QT interval prolongation (ECG monitoring needed).
• 📉 Hematologic: Anemia, thrombocytopenia.
• 🤢 General: Diarrhea, fatigue, muscle pain (myalgia).